Integrative analyses showed associations between microbial composition and host gene expression, such as CD74 positively correlated with Lactobacillus and PPP1R3C negatively with Bacteroidota, suggesting that smoking-induced microbial shifted might interact with host transcriptional programs to promote OSCC progression [59]
The supernatant was collected, and the protein concentration was determined using a protein detection kit (Beyotime Biotechnology, China)
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