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Here are general estimates for how long nicotine and its metabolites can be detected in different bodily systems: Blood: Nicotine can be detected in the bloodstream for about 1 to 3 days after use

Therefore, it is likely that the public health gains obtained from tobacco harm reduction among current smokers would outweigh any population-level harms that result from non-smoker uptake

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The immune response is compromised, leaving the lungs more vulnerable to infection from inhaled particles

Other damage can be reversed in the coming years