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Interestingly, the greatest differences in the composition and abundance of the metabolomes between smokers and non-smokers were among biogenic amines, including, cadaverine (fold change in non-smokers, FC = 53.19), putrescine (FC = 15.80), agmatine (FC = 15.49), tyramine (FC = 5.15) and tryptamine (FC = 4.43), which were much higher in smokers (Table S2, Figure S2)

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In order to reach out to tech-savvy consumers, brands are portraying e-cigarettes and nicotine pouches as lifestyle items and leveraging social media influencers and stylish advertising

DISCUSSION In this study, health warnings on cigarette packaging currently implemented across Australia, Canada, the United Kingdom, and the United States were generally perceived as minimally effective in prompting current smokers to quit, with irrelevance and desensitisation to the warnings being commonly cited

Celebrating Milestones: Progress Acknowledgment: Celebrate milestones, both big and small, in the quitting journey