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Over the last couple of decades, Pratley says, the scientific research community has learned that incretin hormones, including GLP-1, GIP, and others, are important regulators of metabolism with impacts on glycemia, lipids, and body weight
Severe hypoglycemia can cause seizures, loss of consciousness, and requires emergency medical intervention
Thus, we sought to identify a small-molecule GLP-1R agonist that is orally bioavailable using standard formulations, and has the potential to be combined with other oral small molecule therapeutics
LWT 127:109409
This is also seen in hepatic coma, hyperthyroidism, myocardial infarction, megaloblastic anemia, and chronic blood loss
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