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Unlike dyes, which simply coat the hair shaft, an enzyme-based treatment targets the biological cause

SAMe also functions as a precursor molecule for glutathione and promotes polyamine synthesis to promote healthy cellular function

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Symptoms reported at supratherapeutic doses

The other approved anti-fibrotic drug, nintedanib, is a non-specific tyrosine kinase inhibitor, which prevents the phosphorylation multiple targets involved in the development of fibrosis including platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), vascular endothelial growth factor receptor (VEGFR) as well as the type II TGF- receptor (105, 106)