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Conversely, patients with IBS-C may notice worsened constipation initially, since the delayed transit time can extend colonic residence time even further

A visual change is a signal to escalate rather than something to interpret and act on alone

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8 Those who took 100 mg of NR daily experienced a 22% increase in whole blood NAD+ after two weeks, while those taking 1000 mg saw levels rise by 142%

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