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This invariably makes the treatment process laborious and cost-intensive as the patient is less responsive to conventional therapy [33,34,35]

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A key feature is its flexible loop 2, which may serve a gating function for substrate binding specificity

MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL VLKAKGIRHE VININLKNKP EWFFKKNPFG LVPVLENSQG QLIYESAITC EYLDEAYPGK KLLPDDPYEK ACQKMILELF SKVPSLVGSF IRSQNKEDYA GLKEEFRKEF TKLEEVLTNK KTTFFGGNSI SMIDYLIWPW FERLEAMKLN ECVDHTPKLK LWMAAMKEDP TVSALLTSEK DWQGFLELYL QNSPEACDYG L Assay dilution & Images Validation Images & Assay Conditions Click image to see more details 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain