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The likelihood of contamination during repeated use

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Large cohort metagenomic analyses of biopsy-proven NAFLD found that members of Ruminococcaceae are depleted as fibrosis advances in non-obese patients, and follow-up causal experiments showed that oral administration of a human-derived strain, Ruminococcus faecis , reduced serum ALT/AST, diminished collagen deposition and downregulated fibrogenic transcripts (Col1a1, Timp1, -SMA) in multiple mouse NAFLD models (MCD, CDAHFD and db/db), supporting a strain-specific hepatoprotective role (111, 112)

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