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In this study, it was found that MB induces macroautophagy in HT22 hippocampal neuronal cells

nal S, Can ztrk S, Bilgi E, Yank H, Korkusuz P, Akta Y et al (2021) Therapeutic efficacy and gastrointestinal biodistribution of polycationic nanoparticles for oral camptothecin delivery in early and late-stage colorectal tumor-bearing animal model

A phase 3 trial of a higher-dose CagriSema formulation at 2.4/7.2 mg is planned for initiation in the second half of 2026, and the REDEFINE 11 trial, exploring CagriSemas full weight-loss potential, is expected to report data in the first half of 2027

In addition to regulating ferroptosis pathways, flavonoids also target multiple genes and signaling pathways, including nuclear receptors, aryl hydrocarbon receptor (AhR), kinases, receptor tyrosine kinases (RTKs), and G protein-coupled receptors (GPCRs) (Safe et al., 2021)