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Furthermore, incorporating Sarcodon imbricatus or consuming a blend of Angelica gigas, Cnidium officinale, Paeonia lactiflora, moxibustion, cistanche, ginkgo extractsand, and ginseng has shown potential in restoring antioxidant balance and reducing fatigue in ME/CFS models in mice [120,121,122,123,124]

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The phytochemical compounds, particularly terpenoids, have the potential to play an antioxidant role by reducing oxidative stress and scavenging free radicals, as shown in vitro studies (Figure 3)