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3D proximal tubule-on-chip model derived from kidney organoids with improved drug uptake

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Therefore, monitoring of the platelet count and serum potassium concentrations are recommended during therapy

The 1st glutathione-interaction site should be frequently (although transiently) occupied by GSH at millimolar concentrations, whereas diverse non-glutathione disulfide substrates are far less abundant in vivo and should encounter the active site less frequently

Patient assistance programmes : Some pharmaceutical manufacturers offer support schemes, though these are more common outside the UK